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go unnoticed or unrealized for years, often mistaken, undiagnosed, or simply brushed off as simple aging. Because Hypopituitarism refers to a class of Hormone Deficiencies, the symptoms that the patient experiences depend on which hormones are not being produced sufficiently and the severity of that deficiency. Hypopituitarism is a rare disorder in which your pituitary gland fails to produce one or more hormones, or doesn''t produce enough hormones. The pituitary gland is a kidney-bean-sized gland situated at the base of your brain. It is part of your body''s endocrine system, which consists of all the glands that produce and regulate hormones.